Last update: Nov. 23, 2019

Maternal Multiple Sclerosis

Low Risk for breastfeeding

Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

Higher frequency of relapses several months after delivery have been documented. Breastfeeding doesn’t increase the risk of having new episodies of Multiple Sclerosis and some authors think it could lower that risk.

Drugs used for this condition can be set appropriately to compatibilize it with Breastfeeding. Planning strategies for lessening the effect of steroidal megadose are feasible (see medication under specific item).

See below the information of these related products:

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Maternal Multiple Sclerosis is also known as


Maternal Multiple Sclerosis belongs to this group or family:


  1. Langer-Gould AM. Pregnancy and Family Planning in Multiple Sclerosis. Continuum (Minneap Minn). 2019 Jun;25(3):773-792. Abstract
  2. Yalcin SE, Yalcin Y, Yavuz A, Akkurt MO, Sezik M. Maternal and perinatal outcomes in pregnancies with multiple sclerosis: a case-control study. J Perinat Med. 2017 Abstract
  3. Wei W, Liu L, Cheng ZL, Hu B. Increased plasma/serum levels of prolactin in multiple sclerosis: a meta-analysis. Postgrad Med. 2017 Abstract
  4. Smets I, Van Deun L, Bohyn C, van Pesch V, Vanopdenbosch L, Dive D, Bissay V, Dubois B; Belgian Study Group for Multiple Sclerosis.. Corticosteroids in the management of acute multiple sclerosis exacerbations. Acta Neurol Belg. 2017 Abstract
  5. Langer-Gould A, Smith JB, Hellwig K, Gonzales E, Haraszti S, Koebnick C, Xiang A. Breastfeeding, ovulatory years, and risk of multiple sclerosis. Neurology. 2017 Abstract
  6. Jesus-Ribeiro J, Correia I, Martins AI, Fonseca M, Marques I, Batista S, Nunes C, Macário C, Almeida MC, Sousa L. Pregnancy in Multiple Sclerosis: A Portuguese cohort study. Mult Scler Relat Disord. 2017 Abstract
  7. Brenton JN, Engel CE, Sohn MW, Goldman MD. Breastfeeding During Infancy Is Associated With a Lower Future Risk of Pediatric Multiple Sclerosis. Pediatr Neurol. 2017 Abstract
  8. Almas S, Vance J, Baker T, Hale T. Management of Multiple Sclerosis in the Breastfeeding Mother. Mult Scler Int. 2016 Abstract Full text (link to original source) Full text (in our servers)
  9. Alroughani R, Altintas A, Al Jumah M, Sahraian M, Alsharoqi I, AlTahan A, Daif A, Dahdaleh M, Deleu D, Fernandez O, Grigoriadis N, Inshasi J, Karabudak R, Taha K, Totolyan N, Yamout BI, Zakaria M, Bohlega S. Pregnancy and the Use of Disease-Modifying Therapies in Patients with Multiple Sclerosis: Benefits versus Risks. Mult Scler Int. 2016 Abstract Full text (link to original source) Full text (in our servers)
  10. Bove R. Women's Issues in Multiple Sclerosis. Semin Neurol. 2016 Abstract
  11. Fabian M. Pregnancy in the Setting of Multiple Sclerosis. Continuum (Minneap Minn). 2016 Abstract
  12. Strijbos E, Coenradie S, Touw DJ, Aerden L. High-dose methylprednisolone for multiple sclerosis during lactation: Concentrations in breast milk. Mult Scler. 2015 Abstract
  13. AEMPS. Informe de Posicionamiento Terapéutico de dimetilfumarato (Tecfidera). 2015 Full text (in our servers)
  14. Hellwig K, Rockhoff M, Herbstritt S, Borisow N, Haghikia A, Elias-Hamp B, Menck S, Gold R, Langer-Gould A. Exclusive Breastfeeding and the Effect on Postpartum Multiple Sclerosis Relapses. JAMA Neurol. 2015 Oct;72(10):1132-8. Abstract
  15. Houtchens MK, Kolb CM. Multiple sclerosis and pregnancy: therapeutic considerations. J Neurol. 2013 Abstract
  16. Cree BA. Update on reproductive safety of current and emerging disease-modifying therapies for multiple sclerosis. Mult Scler. 2013 Jun;19(7):835-43. Abstract Full text (link to original source) Full text (in our servers)
  17. Lawrence RM. Circumstances when breastfeeding is contraindicated. Pediatr Clin North Am. 2013 Feb;60(1):295-318. Abstract
  18. Hellwig K, Haghikia A, Rockhoff M, Gold R. Multiple sclerosis and pregnancy: experience from a nationwide database in Germany. Ther Adv Neurol Disord. 2012 Sep;5(5):247-53. Abstract Full text (link to original source) Full text (in our servers)
  19. Tsui A, Lee MA. Multiple sclerosis and pregnancy. Curr Opin Obstet Gynecol. 2011 Abstract
  20. Argyriou AA, Makris N. Multiple sclerosis and reproductive risks in women. Reprod Sci. 2008 Abstract
  21. Coyle PK, Christie S, Fodor P, Fuchs K, Giesser B, Gutierrez A, Lynn J, Weinstock-Guttman B, Pardo L; Women Neurologists MS Initiative. Multiple sclerosis gender issues: clinical practices of women neurologists. Mult Scler. 2004 Abstract
  22. Ost L, Wettrell G, Björkhem I, Rane A. Prednisolone excretion in human milk. J Pediatr. 1985 Abstract
  23. Dick G. President's address. The etiology of multiple sclerosis. Proc R Soc Med. 1976 Aug;69(8):611-5. Abstract Full text (link to original source) Full text (in our servers)

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