Last update: Sept. 19, 2016
Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.
We do not have alternatives for Glycerin.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
Main tradenames from several countries containing Glycerin in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 0 (rectal); 100 (oral) | % |
Molecular weight | 92 | daltons |
Tmax | 1,5 | hours |
T1/2 | 0,5 - 0,75 | hours |
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine from United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Glycerin or glycerol is a normal component of human tissues. Involved in lipid and galactose synthesis which is metabolized to glucose or glycogen.
It is found naturally in breast milk, with a highest concentration in colostrum.
When it is used rectally as a laxative, has little or no absorption. It has been used in preterm infants.
The oral or intravenous administration is rarely used (extracellular edema, intracranial hypertension, diagnosis of Meniere's disease). A short half-life span makes it compatible with breastfeeding in these rare cases.
It also compatible with intraocular administration.
It has been used in creams and gels to treat pain and cracks of nipple during lactation without clear results on effectiveness. In those cases it should be cleaned thoroughly with water before the next breast suckling to prevent it could be swallowed by the infant, since a high intestinal absorption may induce an increased plasma osmolality that can result in dehydration of the infant.