Last update: Jan. 19, 2021
Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
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Derived from long-acting benzodiazepines with properties similar to diazepam. Indicated in the short-term treatment of anxiety disorders.
Oral administration once or twice a day.
It is excreted in human milk in a small amount, but it could be clinically significant: RD 6 -12% (Nishimura 2021).
No problems have been observed in infants whose mothers have taken it (Nishimura 2021).
It has very few bibliographical references and is marketed in few countries.
Until there is more published data on this drug in relation to breastfeeding, safer known alternatives are preferable.
It is advisable to choose short-acting benzodiazepines and use the minimum effective dose (Rowe 2013), especially during the neonatal period and in cases of prematurity because they can accumulate in the infant during chronic use (Sachs 2013).
It is advisable to monitor drowsiness and the adequate feeding of the infant.
It is not recommended to share a bed with the baby if this medication is being taken due to an increased risk of suffocation or sudden infant death (UNICEF 2018, 2017, 2014 and 2013, Landa 2012, ABM 2008, UNICEF 2006).
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
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