Last update: Aug. 7, 2019


Low Risk for breastfeeding

Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

A thrombopoietin receptor agonist that increases platelet production. Indicated in the treatment of immune thrombopenic purpura, severe aplastic anemia and hepatitis C.
Administered orally once a day.

Since the last update we have not found published data on its excretion in breastmilk.

Its pharmacokinetic data (high percentage of protein binding and very low pKa) makes transfer to milk in significant amounts unlikely.

Its low oral bioavailability impedes transfer from breastmilk to infant plasma, except in premature infants and the immediate neonatal period when there may be greater intestinal permeability.

In addition, eltrombopag forms chelates with polyvalent ions such as calcium, which significantly reduces the drug’s possible absorption by the infant (EMA 2015)

Its use is authorized in Pediatrics from one year of age (EMA 2015).


We do not have alternatives for Eltrombopag.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Eltrombopag is also known as

Eltrombopag in other languages or writings:


Eltrombopag belongs to this group or family:


Main tradenames from several countries containing Eltrombopag in its composition:


Variable Value Unit
Oral Bioavail. 52 %
Molecular weight 443 daltons
Protein Binding 99,9 %
pKa 3,99 -
Tmax 2 - 6 hours
T1/2 26 - 35 hours


  1. EMA. Eltrombopag. Drug Summary. 2015 Full text (in our servers)
  2. EMA. Eltrombopag. Ficha técnica. 2015 Full text (in our servers)

Total visits


Help us improve this entry

How to cite this entry

Do you need more information or did not found what you were looking for?

   Write to us at

e-lactancia is a resource recommended by AELAMA from Spain

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM