Last update: Aug. 6, 2018
Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
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Indicated in the treatment of infections caused by Mycoplasma pneumoniae, Chlamydia, Rickettsia and spirochetes.
Oral administration once a day.
Excreted into breast milk in quantities that would be clinically significant (Matsuda 1984, Lutziger 1969, Morganti 1968), however, intestinal absorption by infant's gut is hampered because of formation of chelating products by union with the milk's calcium (Chin 2001).
Tetracycline is at lesser amount excreted into breast milk and at higher proportion bound to calcium, hence, it is fewer absorbed than Doxycycline (Hale 2017 p312, Chin 2001).
Long-term treatments are not recommended (over 3-4 weeks) since it may cause damage of the growth cartilage, teeth discoloration and imbalance of intestinal flora.
Several medical societies, experts and expert consensus, consider the use of this medication safe or probably safe during breastfeeding (Hale 2017 p312, Briggs 2017, Rowe 2013, Chen 2010, Mitrano 2009, Nahum 2006, Mahadevan 2006, WHO 2002, Chin 2001).
Be aware of false negative results of bacterial cultures obtained from febrile infants whose mothers are on antibiotics, as well as the possibility of gastroenteritis due to altered intestinal flora (Briggs 2017, Ito 1993).
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
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