Last update: July 15, 2017


Very Low Risk for breastfeeding

Safe. Compatible.
Minimal risk for breastfeeding and infant.

Synthetic progesterone. Used for the treatment of endometriosis.
In association with estrogen it has been used as a birth-control medication (e.g. Estradiol + Dienogest)

A latest update no published data on excretion into breast milk were found. Progesterone and other related progestin drugs are excreted into breast milk in clinically non-significant amount, and, no problems have been observed in infants whose mothers were treated with this medication. Plasma levels of these infants were usually very low.

It has been occasionally observed an increase of prolactin with increased milk production, however, it would be advisable to start taking it until breastfeeding is well established (first 4 to 6 weeks postpartum).

See below the information of this related product:


Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Dienogest in other languages or writings:


Dienogest belongs to this group or family:


Main tradenames from several countries containing Dienogest in its composition:


Variable Value Unit
Oral Bioavail. 91 %
Molecular weight 311 daltons
Protein Binding 90 %
VD 0,55 l/Kg
Tmax 1,5 hours
T1/2 10 - 14 hours


  1. AEMPS. Dienogest. Ficha técnica. 2015 Full text (in our servers)
  2. Okada H, Nakajima T, Yoshimura T, Yasuda K, Kanzaki H. The inhibitory effect of dienogest, a synthetic steroid, on the growth of human endometrial stromal cells in vitro. Mol Hum Reprod. 2001 Abstract

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e-lactancia is a resource recommended by La Liga de la Leche de Euskadi

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