Last update: Nov. 16, 2019
Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.
Relaxant drug of the muscle with action on the Central Nervous System and chemically related to tricyclic antidepressants.
Indicated in muscle spasms of musculoskeletal origin.
Oral administration one to three times a day, maximum 2 weeks.
Its pharmacokinetic data (large volume of distribution and high percentage of protein binding) explain the very small passage to milk observed (Burra 2019).
No problems have been observed in two infants whose mothers took it for months since birth (Burra 2019).
A 16-day-old newborn whose mother took cyclobenzaprine, paracetamol and oxycodone had recoverable cardiorespiratory problems (Beauchamp 2019).
It is recommended to use the lowest effective dose possible.
Long-term treatments or those mothers who are nursing a newborn or premature infant would be prudent the use of a known safer alternative or with a shorter elimination half life.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
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