Last update: July 11, 2016

Chloropyramine Hydrochloride

High Risk for breastfeeding

Poorly safe. Evaluate carefully.
Use safer alternative or interrupt breastfeeding 3 to 7 T ½ (elimination half-lives).
Read the Comment.

First generation antihistamine drug which is derived from ethylene diamine with important sedative and antimuscarinic effects. The anticholinergic effect may inhibit lactation.

At latest update no published data on excretion into breast milk was found.

Drug that is scarcely supported by bibliographical evidence, which is marketed in very few countries from Eastern Europe, Mexico ...

Until more published information about this drug regarding breastfeeding appears, it may be preferable the use of a known and safer alternative.


Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Chloropyramine Hydrochloride is also known as

Chloropyramine Hydrochloride in other languages or writings:


Chloropyramine Hydrochloride belongs to this group or family:


Main tradenames from several countries containing Chloropyramine Hydrochloride in its composition:


Variable Value Unit
Oral Bioavail. 100 %
Molecular weight 326 daltons
VD 7,9 l/Kg
Tmax 1 - 2 hours
T1/2 3 - 6 hours


  1. Online Medicina. Suprastin. Prospecto. 2010 Full text (in our servers)

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