Last update: July 11, 2017

Chlormadinone Acetate

Very Low Risk for breastfeeding

Safe. Compatible.
Minimal risk for breastfeeding and infant.

Synthetic progestin-related drug similar to the progesterone used for treatment of uterine bleeding, dysmenorrhea, infertility and occasionally for prostate problems.
It has been used as a birth control medication, as single component or in combination with estrogen (e.g. mestranol + chlormadinone).

No changes in prolactin were observed on plasma levels or milk production in women treated with chlormadinone.

During lactation progestin-only drugs are preferred or in combination with estrogen for birth control, but whatever, the ones with the lower doses of estrogen should be used.
For the first 6 weeks postpartum, non-hormonal methods are of choise.

See below the information of this related product:


Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Chlormadinone Acetate in other languages or writings:


Chlormadinone Acetate belongs to these groups or families:


Main tradenames from several countries containing Chlormadinone Acetate in its composition:


Variable Value Unit
Molecular weight 405 daltons


  1. Beck P, Malarkey WB. Serum prolactin concentrations in women treated with chlormadinone acetate. Am J Obstet Gynecol. 1976 Abstract
  2. Pilawski Z, Olszewska D, Piernikowski Z, Pronicki B. [Lactation inhibition with chlormadinone and mestranol]. Wiad Lek. 1973 Abstract
  3. Sammour MB, Ramadan ME, Salah M. Effect of chlormadinone on the composition of human milk. Fertil Steril. 1973 Abstract
  4. González C. [Continuous microdoses of chloramadinone during lactation]. Ginecol Obstet Mex. 1970 Abstract
  5. Cásares Ponce HJ. [Daily administration of microdoses of chlormadinone and its effects on breast feeding]. Ginecol Obstet Mex. 1969 Abstract
  6. Howard G, Blair M, Elstein M, Morris NF. Low-dose continuous chlormadinone acetate as an oral contraceptive. A clinical trial. Lancet. 1969 Abstract
  7. Martinez-Manautou J, Giner-Velasquez J, Cortes-Gallegos V, Aznar R, Rojas B, Guitterez-Najar A, Rudel HW. Daily progestogen for contraception: a clinical study. Br Med J. 1967 Abstract Full text (link to original source) Full text (in our servers)

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