Last update: Oct. 20, 2016

Bifonazole

Very Low Risk for breastfeeding


Safe. Compatible.
Not risky for breastfeeding or infant.

Topical antifungal medication which is indicated for the treatment of mycosis of skin and nails.

At latest update relevant published data were not found on excretion into breast milk.

A negligible systemic absorption through the skin - less than 1% on intact skin and up to 4% on inflamed skin (Fromtling 1988) - makes very unlikely that significant amounts would be excreted into breast milk.

Do not apply on the breast to prevent ingestion by the infant; otherwise, do it just after a meal and clean the nipple thoroughly with water before the next feed.

Local application on the nipple of creams, gels and other products containing paraffin (mineral oil) should better be avoid to keep the infant off from absorption (Noti 2003, Concin 2008).

Alternatives

We do not have alternatives for Bifonazole since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Bifonazole is also known as


Bifonazole in other languages or writings:

Group

Bifonazole belongs to this group or family:

Tradenames

Main tradenames from several countries containing Bifonazole in its composition:

Pharmacokinetics

Variable Value Unit
Bioavailability <1 a 4 %
Molecular weight 311 daltons
T1/2 19 - 32 hours

References

  1. AEMPS. Bifonazol. Ficha técnica. 2016 Full text (in our servers)
  2. Bayer. Bifonazole. Drug Summary. 2009 Full text (in our servers)
  3. Noti A, Grob K, Biedermann M, Deiss U, Brüschweiler BJ. Exposure of babies to C15-C45 mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003 Abstract
  4. Fromtling RA. Overview of medically important antifungal azole derivatives. Clin Microbiol Rev. 1988 Abstract Full text (link to original source) Full text (in our servers)
  5. Lücker PW, Beubler E, Kukovetz WR, Ritter W. Retention time and concentration in human skin of bifonazole and clotrimazole. Dermatologica. 1984 Abstract

Total visits

20,415

Help us improve this entry

How to cite this entry

Do you need more information or did not found what you were looking for?

   Write to us at elactancia.org@gmail.com

e-lactancia is a resource recommended by Academy of Breastfeeding Medicine from United States of America

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM