Last update: Aug. 12, 2014

Atropine

Very Low Risk for breastfeeding


Safe. Compatible.
Not risky for breastfeeding or infant.

Either isolated dose or topical medication are safe for breastfed babies.

Anti-cholinergic drugs decrease Prolactin and Oxytocin hormone secretion. Long-standing Atropine treatment could affects mother's milk production.

American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.

Alternatives

We do not have alternatives for Atropine since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Tradenames

Main tradenames from several countries containing Atropine in its composition:

  • Atropinol
  • Atropisol
  • Atropt
  • Barbidonna
  • Buton™. Contains other elements than Atropine in its composition
  • Causat™. Contains other elements than Atropine in its composition
  • Colestase™. Contains other elements than Atropine in its composition
  • Colicor™. Contains other elements than Atropine in its composition
  • Dipatropin™. Contains other elements than Atropine in its composition
  • Dolospam™. Contains other elements than Atropine in its composition
  • Dymotil™. Contains other elements than Atropine in its composition
  • Lofenoxal™. Contains other elements than Atropine in its composition
  • Logen™. Contains other elements than Atropine in its composition
  • Lomotil™. Contains other elements than Atropine in its composition
  • Migrane™. Contains other elements than Atropine in its composition
  • Neo-Diophen™. Contains other elements than Atropine in its composition
  • Retardin™. Contains other elements than Atropine in its composition
  • Yanal™. Contains other elements than Atropine in its composition

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 90 %
Molecular weight 289 daltons
Protein Binding 14 %
Tmax 1 hours
T1/2 4,3 hours

References

  1. Reece-Stremtan Sarah, Campos Matilde, Kokajko Lauren, and The Academy of Breastfeeding Medicine. Breastfeeding Medicine. ABM Clinical Protocol #15: Analgesia and Anesthesia for the Breastfeeding Mother, Revised 2017. Breastfeed Med. 2017 Nov;12(9):500-506. Full text (link to original source) Full text (in our servers)
  2. Chen LH, Zeind C, Mackell S, LaPointe T, Mutsch M, Wilson ME. Breastfeeding travelers: precautions and recommendations. J Travel Med. 2010 Jan-Feb;17(1):32-47. Abstract Full text (link to original source) Full text (in our servers)
  3. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Full text (link to original source) Full text (in our servers)
  4. AAP - American Academy of Pediatrics Committee on Drugs. Transfer of drugs and other chemicals into human milk. Pediatrics. 2001 Sep;108(3):776-89. Abstract Full text (link to original source) Full text (in our servers)
  5. Hagemann TM. Gastrointestinal medications and breastfeeding. J Hum Lact. 1998 Sep;14(3):259-62. Review. Abstract
  6. Lee JJ, Rubin AP. Breast feeding and anaesthesia. Anaesthesia. 1993 Jul;48(7):616-25. Review. Abstract Full text (link to original source) Full text (in our servers)
  7. De Martino F, De Matteo A, L'Abbate V, Soricelli A, Fontana A, Petrenga E, Cesarone M. [Inhibitory effects of atropine on serum prolactin levels after TRH stimulation]. Boll Soc Ital Biol Sper. 1980 Abstract
  8. Bizzarro A, Iannucci F, Tolino A, Soricelli A, Guarino G, Verdoliva A. Inhibiting effect of atropine on prolactin blood levels after stimulation with TRH. Clin Exp Obstet Gynecol. 1980 Abstract

Total visits

18,515

Help us improve this entry

How to cite this entry

Do you need more information or did not found what you were looking for?

   Write to us at elactancia.org@gmail.com

e-lactancia is a resource recommended by La Liga de la Leche de México from Mexico

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM