Last update: Dec. 19, 2013


Very Low Risk for breastfeeding

Safe. Compatible.
Minimal risk for breastfeeding and infant.

Topical ophthalmologic anti-histaminic drug that achieves very low plasma concentration with only 60 pg/mL. Hence, an insignificant excretion into breast milk should be advanced.


We do not have alternatives for Alcaftadine since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.


Alcaftadine belongs to this group or family:


Main tradenames from several countries containing Alcaftadine in its composition:


Variable Value Unit
Molecular weight 307 daltons
Protein Binding 39 - 63 %
Tmax 0,25 hours
T1/2 2 hours
Theoretical Dose < 0,00001 mg/Kg/d


  1. Bohets H, McGowan C, Mannens G, Schroeder N, Edwards-Swanson K, Shapiro A. Clinical pharmacology of alcaftadine, a novel antihistamine for the prevention of allergic conjunctivitis. J Ocul Pharmacol Ther. 2011 Abstract
  2. Alcaftadina. Ficha técnica. 2011 Full text (in our servers)
  3. Alcaftadine. Data Sheet. 2011 Full text (in our servers)

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e-lactancia is a resource recommended by Instituto de Salud Infantil, Grecia-Institute of Child's Health in Greece

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM