Last update: Nov. 15, 2015
Minimal risk for breastfeeding and infant.
Used as a systemic drug for cardiac resuscitation and locally in topical anesthetic preparations, epidural anesthesia, eye drops (mydriatic), and nasal drops (vasoconstrictor).
At last update no published data on excretion in breast milk were found.
Its rapid metabolism (short Tmax and T½) makes it unlikely an excretion into milk in significant amounts.
It is destroyed in the gastrointestinal tract. The low oral-bioavailability makes its levels into infant's plasma, that would be absorbed from ingested breast milk, be nil or negligible.
Maintained high intravenous doses decrease milk production by interfering with the secretion of prolactin especially the early postpartum-weeks, because when breastfeeding is well established, prolactin levels do not correlate with milk production any longer.
No problems related to lactation have been observed due to epidural anesthesia in which adrenaline is used.
We do not have alternatives for Adrenaline since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
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