Last update: Aug. 6, 2017

Acarbose

Very Low Risk for breastfeeding


Safe. Compatible.
Not risky for breastfeeding or infant.

Alpha-glucosidase inhibitor which acts within the gastrointestinal tract without being absorbed, reducing intestinal absorption of glucose. Very low risk of hypoglycemia in monotherapy.

Since the last update we have not found any published data on its excretion in breast milk.

Its pharmacokinetic data (moderately elevated molecular weight and very low intestinal absorption) make it unlikely that it would pass to breast milk in significant amounts (Serrano 2014, Everett 1997).

Diet, exercise, and breastfeeding improve blood sugar levels.


See below the information of this related product:

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Acarbose is also known as


Acarbose in other languages or writings:

Tradenames

Main tradenames from several countries containing Acarbose in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 0,7 - 2 %
Molecular weight 646 daltons
VD 0,3 l/Kg
Tmax 1 hours
T1/2 2 - 3 hours

References

  1. Serrano Aguayo P, García de Quirós Muñoz JM, Bretón Lesmes I, Cózar León MV. Tratamiento de enfermedades endocrinológicas durante la lactancia. [Endocrinologic diseases management during breastfeeding.] Med Clin (Barc). 2015 Abstract
  2. Davis C. Acarbose. Drug Summary. 2015 Full text (in our servers)
  3. AEMPS. Acarbosa. Ficha técnica. 2009 Full text (in our servers)
  4. Everett JA. Use of oral antidiabetic agents during breastfeeding. J Hum Lact. 1997 Abstract
  5. Ahr HJ, Krause HP, Siefert HM, Steinke W, Weber H. Pharmacokinetics of acarbose. Part II: Distribution to and elimination from tissues and organs following single or repeated administration of [14C]acarbose to rats and dogs. Arzneimittelforschung. 1989 Abstract
  6. Ahr HJ, Boberg M, Krause HP, Maul W, Müller FO, Ploschke HJ, Weber H, Wünsche C. Pharmacokinetics of acarbose. Part I: Absorption, concentration in plasma, metabolism and excretion after single administration of [14C]acarbose to rats, dogs and man. Arzneimittelforschung. 1989 Abstract

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