Last update Dec. 26, 2023

异美汀 

Limited compatibility

Unsafe. Moderate/severe adverse effects. Compatible under certain circumstances. Follow-up recommended. Use safer alternative or discontinue breastfeeding from 5 to 7 T ½ . Read Commentary.

Isometheptene is a sympathomimetic with vasoconstrictor effect used to relieve painful spasms of migraine attacks in combination with other agents such as caffeine and metamizole. Oral administration.

At the time of the last update we found no published data on its excretion in breast milk.

Product with very few bibliographic references and/or very outdated, marketed in only a few countries.

The scarcity of known pharmacokinetic data does not allow predicting its possible excretion in breast milk.

Safer known alternatives are preferable during lactation, especially during the neonatal period and in case of prematurity.

Alternatives

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

异美汀  is Isometheptene in Chinese.

Is written in other languages:

异美汀  is also known as

Group

异美汀  belongs to this group or family:

Tradenames

Main tradenames from several countries containing 异美汀  in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 493 daltons

References

  1. Duong S, Bozzo P, Nordeng H, Einarson A. Safety of triptans for migraine headaches during pregnancy and breastfeeding. Can Fam Physician. 2010 Abstract Full text (link to original source) Full text (in our servers)
  2. Jürgens TP, Schaefer C, May A. Treatment of cluster headache in pregnancy and lactation. Cephalalgia. 2009 Abstract
  3. Beseler-Soto B, Paricio-Talayero JM, Sánchez-Palomares M, Benlloch-Muncharaz M, Santos-Serrano L, Landa-Rivera L. MIgraña en la mujer. [Migraine and female]. Rev Neurol. 2008 Abstract
  4. Raña-Martínez N. Migraña en la mujer. [Migraine in females]. Rev Neurol. 2008 Abstract
  5. MacGregor EA. Migraine in pregnancy and lactation: a clinical review. J Fam Plann Reprod Health Care. 2007 Abstract Full text (link to original source) Full text (in our servers)
  6. Loder E. Migraine in pregnancy. Semin Neurol. 2007 Abstract
  7. Sances G, Granella F, Nappi RE, Fignon A, Ghiotto N, Polatti F, Nappi G. Course of migraine during pregnancy and postpartum: a prospective study. Cephalalgia. 2003 Abstract
  8. Wojnar-Horton RE, Hackett LP, Yapp P, Dusci LJ, Paech M, Ilett KF. Distribution and excretion of sumatriptan in human milk. Br J Clin Pharmacol. 1996 Abstract Full text (link to original source) Full text (in our servers)

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