Last update June 27, 2022
It is a bicyclic antidepressant. Used in the treatment of depression and attention deficit hyperactivity disorder (ADHD) in adults and children. Oral administration once daily.
Since the last update we have not found published data on its excretion in breastmilk.
Its pharmacokinetic data do not allow predicting the possible excretion in breast milk: while its high distribution volume would make it difficult, its low protein binding and low molecular weight would favor it.
May cause drowsiness, fatigue, irritability, and suicidal ideation. (FDA 2021)
Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable, especially during the neonatal period and in the event of prematurity.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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