Last update June 27, 2022

Вилоксазина Гидрохлорид

Limited compatibility

Unsafe. Moderate/severe adverse effects. Compatible under certain circumstances. Follow-up recommended. Use safer alternative or discontinue breastfeeding from 5 to 7 T ½ . Read Commentary.

It is a bicyclic antidepressant. Used in the treatment of depression and attention deficit hyperactivity disorder (ADHD) in adults and children. Oral administration once daily.

Since the last update we have not found published data on its excretion in breastmilk.

Its pharmacokinetic data do not allow predicting the possible excretion in breast milk: while its high distribution volume would make it difficult, its low protein binding and low molecular weight would favor it.

May cause drowsiness, fatigue, irritability, and suicidal ideation. (FDA 2021)

Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable, especially during the neonatal period and in the event of prematurity.


  • Dexamfetamine Sulfate (Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.)
  • Methylphenidate (Safe substance and/or breastfeeding is the best option.)
  • Paroxetine (Safe substance and/or breastfeeding is the best option.)
  • Sertraline Hydrochloride (Safe substance and/or breastfeeding is the best option.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Вилоксазина Гидрохлорид is Viloxazine Hydrochloride in Cyrillic.

Is written in other languages:


Вилоксазина Гидрохлорид belongs to these groups or families:


Main tradenames from several countries containing Вилоксазина Гидрохлорид in its composition:


Variable Value Unit
Oral Bioavail. 88 %
Molecular weight 274 daltons
Protein Binding 76 - 82 %
VD 0.73 ± 0.28 l/Kg
Tmax 5 (3 - 9) hours
7.0 ± 4.7 hours


  1. FDA. Viloxazine (Qelbree). Frug Summary. 2021 Full text (in our servers)

Total visits


Help us improve this entry

How to cite this entry

Do you need more information or did not found what you were looking for?

   Write us at

e-lactancia is a resource recommended by El Parto Es Nuestro of Spain

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM