Last update June 23, 2022
Compatible
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Triphthazinum is also known as Trifluoperazine Hydrochloride. Here it is a list of alternative known names::
Triphthazinum in other languages or writings:
Triphthazinum belongs to these groups or families:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | Alta - Hig | % |
Molecular weight | 480 | daltons |
Protein Binding | 90 - 99 | % |
Tmax | 2 - 4 | hours |
T½ | 10 - 20 | hours |
M/P ratio | 0 | - |
Theoretical Dose | 0 | mg/Kg/d |
Relative Dose | 0 | % |
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Typical, first generation antipsychotic, phenothiazine, with pharmacological action similar to chlorpromazine. Used in the treatment of schizophrenia and other psychoses. It is also useful in the treatment of nausea and vomiting of central origin. Oral administration in 2 daily doses.
It is excreted in breast milk in clinically insignificant amounts. (Yoshida 1998)
No problems have been observed in infants whose mothers have taken it. (Goldstein 2000, Birnbaum 1999, Yoshida 1998)
Urine levels in one infant were very low. (Yoshida 1998)
Like other phenothiazines, it can cause hyperprolactinemia and produce galactorrhea. (Gruen 1978, Meltzer 1976, Hussain 1972)
Some authors consider it very safe during lactation (Parikh 2014). Until more published data is known about this drug in relation to breastfeeding, known safer alternatives may be preferable (Hale, LactMed, Uguz 2021, Parikh 2014, Klinger 2013), especially during the neonatal period and in the event of prematurity.
See below the information of this related product: