Last update Jan. 29, 2022
Very Low Risk
A short-term action Sulfonamide which is similar to Sulfathiazole that is locally used on vagina, eyes and skin.
At latest update relevant published data were not found on excretion into breast milk.
Because of the small dose used and poor absorption into plasma of most topical preparations for dermatological and ophthalmological issues, it is unlikely a significant excretion into breast milk.
Sulphamides are excreted in small amounts in breast milk: 6 to 94 micrograms/ml, 1.6% of the total dose and reports of adverse effects are rare. (Briggs 2015)
As with other sulfonamides, caution is recommended when using it on preterm infants and newborns with hyperbilirubinemia. Avoid it on patients affected with deficit of Glucose 6-Phosphate Dehydrogenase (6-GPD). Monitor the appearance of jaundice in the infant. (FDA 2015, Taro 2012)
Do not apply to the breast in order to prevent the infant from ingesting it; if necessary, apply after a feed and clean well with water before the next one.
Due to the greater toxicity than other antimicrobials and their high acquired resistance, the use of sulfonamides is currently very scarce. (Pérez 2003)
We do not have alternatives for Sulfacetamide since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2012 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM