Last update Jan. 29, 2022

Sulfacetamide

Compatible

Safe product and/or breastfeeding is the best option.

A short-term action Sulfonamide which is similar to Sulfathiazole that is locally used on vagina, eyes and skin.

At latest update relevant published data were not found on excretion into breast milk.

Because of the small dose used and poor absorption into plasma of most topical preparations for dermatological and ophthalmological issues, it is unlikely a significant excretion into breast milk.

Sulphamides are excreted in small amounts in breast milk: 6 to 94 micrograms/ml, 1.6% of the total dose and reports of adverse effects are rare. (Briggs 2015)

As with other sulfonamides, caution is recommended when using it on preterm infants and newborns with hyperbilirubinemia. Avoid it on patients affected with deficit of Glucose 6-Phosphate Dehydrogenase (6-GPD). Monitor the appearance of jaundice in the infant. (FDA 2015, Taro 2012)

Do not apply to the breast in order to prevent the infant from ingesting it; if necessary, apply after a feed and clean well with water before the next one.

Due to the greater toxicity than other antimicrobials and their high acquired resistance, the use of sulfonamides is currently very scarce. (Pérez 2003)


See below the information of this related product:

  • Sulfathiazole (Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.)

Alternatives

We do not have alternatives for Sulfacetamide since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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José María Paricio, founder of e-lactancia.
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Other names

Sulfacetamide is also known as


Sulfacetamide in other languages or writings:

Groups

Sulfacetamide belongs to these groups or families:

Tradenames

Main tradenames from several countries containing Sulfacetamide in its composition:

List of 15 tradenames

Pharmacokinetics

Variable Value Unit
Oral Bioavail. Cut: 4% %
Molecular weight 214 daltons
Protein Binding 80 - 85 %
T½ 7 - 13 hours

References

  1. FDA. Sodium Sulfacetamide. FDA prescribing information, side effects and uses. 2015 Full text (in our servers)
  2. Briggs GG, Freeman RK, Towers CV, Forinash AB. Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk. Wolters Kluwer Health. Tenth edition (acces on line) 2015
  3. Taro Pharmaceuticals U.S.A., Inc. Sulfacetamide. Drug Summary. 2012 Full text (in our servers)
  4. Pérez-Trallero E, Iglesias L. Tetraciclinas, sulfamidas y metronidazol. [Tetracyclines, sulfonamides and metronidazole]. Enferm Infecc Microbiol Clin. 2003 Nov;21(9):520-8; quiz 529, 533. Review. Spanish. Abstract Full text (link to original source)

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