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Sotalol is a noncardioselective beta-blocker used to treat life-threatening ventricular arrhythmias and to maintain sinus rhythm in atrial fibrillation or flutter. Oral or intravenous administration.
It is excreted in breast milk in an amount that could be significant due to reaching a relative dose > 20%. (Wagner 1990, Hackett 1990, O'Hare 1980)
No problems have been observed in infants whose mothers have taken it. (Ho 1999, Hackett 1990)
Some authors consider it a medication moderately acceptable with important reservations during breastfeeding (Malachias 2016, Tan 2001). American Academy of Pediatrics: medication usually compatible with breastfeeding. (AAP 2001)
Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable (Hale, LactMed), especially during the neonatal period and in the event of prematurity.