Last update July 31, 2018
Likely Compatibility
We do not have alternatives for Silodosin.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Thank you for helping to protect and promote breastfeeding.
Silodosin is also known as
Silodosin in other languages or writings:
Silodosin belongs to this group or family:
Main tradenames from several countries containing Silodosin in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 32 | % |
Molecular weight | 496 | daltons |
Protein Binding | 96.6 | % |
VD | 0.81 | l/Kg |
pKa | 14.9 | - |
Tmax | 2.5 ( 1 - 3 ) | hours |
T½ | 11 - 24 | hours |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by El Parto Es Nuestro of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Alpha-1 adrenergic blocker indicated in benign prostatic hyperplasia (BPH) in adult males.
Oral administration once a day.
Since the last update we have not found published data on its excretion in breastmilk.
Its high percentage of protein binding (EMA 2018) makes transfer into milk in significant amounts unlikely.
Its low oral bioavailability, reduced further with the consumption of fatty foods, such as milk (EMA 2018), hinders its transfer to the infant’s plasma from the breastmilk ingested, except in premature babies and the immediate neonatal period when there may be greater intestinal permeability.
Possible side effects are not serious or frequent (EMA 2018).