Join our newsletter
Get updated info, tips and news about breastfeeding, e-lactancia project and other initiatives from APILAM
Legitimation: Consent of the interested party
As a user and interested I inform you that the data you provide will be located on the servers of MailChimp (email marketing provider of APILAM) outside the EU in the USA. MailChimp is covered by the EU-US Privacy Shield agreement, whose information is available here, approved by the European Committee for Data Protection. See Mailchimp's privacy policy. (https://mailchimp.com/legal/privacy/).
The fact that you do not enter the personal data that appear on the form as mandatory may have the consequence that we can not meet your request.
You can exercise your rights of access, rectification, limitation and delete the data in apilam.es@gmail.com as well as the right to file a claim with a control authority.
You can consult the additional and detailed information on Data Protection on this website: http://e-lactancia.org, as well as consult our own privacy policy.
Quinupristin and dalfopristin are streptogramin antibacterial semisynthetic derivatives of pristinamycin I and IIA. They are used in combination in a 3:7 ratio for the treatment of severe infections with multidrug-resistant gram-positive bacteria, specifically MRSA and vancomycin-resistant Enterococcus faecium. Intravenous administration every 8 to 12 hours.
At the time of the last update, we found no published data on its excretion in breast milk.
Its pharmacokinetic data (high molecular weight and large volume of distribution) make it unlikely to pass into breast milk in clinically significant quantities (Hale, Mitrano 2009, Chin 2000), although the low binding to plasma proteins could favor it.
Its low oral bioavailability makes it difficult for it to pass into infant plasma from ingested breast milk, except in premature infants and the immediate neonatal period in which there may be greater intestinal permeability.
Monitor the appearance of vomiting, diarrhea or jaundice in the infant. Although rare, the possibility of transient gastroenteritis due to altered intestinal flora in infants whose mothers take antibiotics should be considered. (Briggs 2015, Ito 1993)
Until more published data on this drug in relation to lactation are known, safer alternatives may be preferable, especially during the neonatal period and in case of prematurity.
See below the information of this related product: