Last update Oct. 20, 2016

Pyrantel Embonate

Compatible

Safe substance and/or breastfeeding is the best option.

Anthelmintic drug which is effective against intestinal nematodes (Ascaris lumbricoides, Enterobius vermiculaires, -pinworms-, Trichostrongylus spp, Ancylostoma or Necator -hookworms) and tissue nematodes.

At latest update relevant published data were not found on excretion into breast milk.

It is poorly absorbed from the gastrointestinal tract, reaching very low plasma concentrations (<0.04 micrograms / mL: Fasanmade 1994) and usually given on a single dose, so it will hardly reach a significant concentrations in breastmilk.
Given its minimum absorption, it has been authorized to be used in young infants.

WHO List of Essential Medicines 2002: compatible with breastfeeding.

Alternatives

We do not have alternatives for Pyrantel Embonate since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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Other names

Pyrantel Embonate is also known as


Pyrantel Embonate in other languages or writings:

Group

Pyrantel Embonate belongs to this group or family:

Tradenames

Main tradenames from several countries containing Pyrantel Embonate in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. < 50 %
Molecular weight 595 daltons
Tmax 1 - 3 hours

References

  1. Porto I. Antiparasitic drugs and lactation: focus on anthelmintics, scabicides, and pediculicides. J Hum Lact. 2003 Abstract
  2. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Abstract Full text (link to original source) Full text (in our servers)
  3. Fasanmade AA, Akanni AO, Olaniyi AA, Fasanmade AA, Tayo F. Bioequivalence of pyrantel pamoate dosage forms in healthy human subjects. Biopharm Drug Dispos. 1994 Abstract

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