Last update Nov. 8, 2024

Пирантела Эмбонат

Compatible

Safe product and/or breastfeeding is the best option.

Pyrantel is a pyrimidine-derived anthelmintic agent for the oral treatment of various parasitic infections, including ascariasis, hookworm infections, enterobiasis (pinworm infection), trichostrongyliasis and trichinellosis. Oral administration in single or repeated doses after two weeks. Some helminths require treatments of 3 to 4 days.

At the date of the last update we found no published data on its excretion in breast milk.

Given its low gastrointestinal absorption, reaching very low plasma concentrations, < 0.04 micrograms/mL (Fasanmade 1994), which hinders both the passage into the mother's plasma, and therefore into breast milk, and into the infant's plasma from ingested breast milk, the short period of treatment required and the benign nature of the possible side effects, expert authors consider it acceptable during breastfeeding. (LactMed)

Authorized in infants from 6 months of age.

WHO list of essential medicines: compatible with breastfeeding. (WHO-UNICEF 2002)

Alternatives

  • Albendazole (Safe product and/or breastfeeding is the best option.)
  • Mebendazole (Safe product and/or breastfeeding is the best option.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Пирантела Эмбонат is Pyrantel Embonate in Cyrillic.

Is written in other languages:

Пирантела Эмбонат is also known as

Group

Пирантела Эмбонат belongs to this group or family:

Tradenames

Main tradenames from several countries containing Пирантела Эмбонат in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. baja / poor %
Molecular weight 595 daltons
Tmax 1 - 3 hours

References

  1. Porto I. Antiparasitic drugs and lactation: focus on anthelmintics, scabicides, and pediculicides. J Hum Lact. 2003 Abstract
  2. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Abstract Full text (link to original source) Full text (in our servers)
  3. Fasanmade AA, Akanni AO, Olaniyi AA, Fasanmade AA, Tayo F. Bioequivalence of pyrantel pamoate dosage forms in healthy human subjects. Biopharm Drug Dispos. 1994 Abstract

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