Last update Aug. 6, 2018

Pridinol Mesilate

High Risk

Poorly safe. Evaluate carefully. Use safer alternative or interrupt breastfeeding 3 to 7 T ½ (elimination half-lives). Read the Comment.

Centrally acting muscle relaxant with anticholinergic effects.

At last update no published on excretion in breast milk data were found. Even on humans pharmacokinetic data is barely found.

Its anticholinergic effect has a theoretical risk of inhibiting lactation especially during the early postpartum weeks.

Until more data about this drug regarding breastfeeding is available, safer known alternatives should be of choice, especially in the neonatal period and in case of prematurity.

If administered during breastfeeding, use small doses and monitor drowsiness and adequate feeding of the infants.

(Not to be confused with the trademark Pridinol, which in some countries corresponds to Terfenadine)

Alternatives

  • Baclofen ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Methocarbamol (Possibly safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Pridinol Mesilate in other languages or writings:

Group

Pridinol Mesilate belongs to this group or family:

Tradenames

Main tradenames from several countries containing Pridinol Mesilate in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 392 daltons
Tmax 0.5 - 0.7 hours

References

  1. Bago. Pridinol. Ficha técnica. 2000 Full text (in our servers)

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