Last update March 16, 2021
Very Low Risk
An osmotic laxative which is not absorbed.
Polymers whose molecular weight is between 1,000 and 35,000 daltons. The number added to the term "macrogol" defines its molecular weight, eg: macrogol 3350.
Since the last update we have not found published data on its excretion in breast milk.
Its pharmacokinetic data (zero oral bioavailability and high molecular weight) make transfer to milk in significant quantities unlikely.
Its zero oral bioavailability prevents its transfer to the infant’s plasma via ingested breast milk.
Experts and scientific associations, as well as the manufacturer, consider it compatible with breastfeeding (Gharehbaghi 2016, Müller 2013, AEMPS 2010, Mahadevan 2006).
We do not have alternatives for Polyethylene Glycol (PEG) since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it.
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