Last update Dec. 1, 2004

Pizotifen

Low Risk

Moderately safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.

It is a first generation antihistaminic and piperidine drug with a moderately sedative effect. Minimally secreted into breast milk. Indicated for anorexia (Cyproheptadine is safer) and long-term prophylaxis of migraine (Propranolol or Valproate are considered to be safer drugs)

Alternatives

  • Cyproheptadine-Hcl (Moderately safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.)
  • Hydroxyzine (Moderately safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.)
  • Propranolol ( Safe. Compatible. Minimal risk for breastfeeding and infant.)
  • Valproic Acid, Valproate ( Safe. Compatible. Minimal risk for breastfeeding and infant.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Pizotifen is also known as


Group

Pizotifen belongs to this group or family:

Tradenames

Main tradenames from several countries containing Pizotifen in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. Alta - Hig %
Molecular weight 295 daltons
Protein Binding 90 %
Tmax 5 hours
23 hours

References

  1. Davanzo R, Bua J, Paloni G, Facchina G. Breastfeeding and migraine drugs. Eur J Clin Pharmacol. 2014 Abstract

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