Last update Aug. 6, 2022
It is a non-depolarizing muscle relaxant drug with a peripheral action that is used as premedication for endotracheal intubation, general anesthesia and mechanical ventilation. Intravenous administration.
At latest update, no relevant published data concerning excretion into breast milk were found.
Because a relatively high molecular-weight and a high protein-binding capacity, excretion into breast milk is thought to be low.
Also, quaternary ammonium muscle relaxants are poorly absorbed from the gastro-intestinal tract; its low oral bioavailability renders the pass of this agent to the infant's plasma highly unlikely. (Dalal 2014, Spigset 1994)
Pancuronium does not prevent a mother from breast feeding her baby shortly after recovering from anesthesia if she is awake and in good condition.
Experts authors consider the use of this medication to be probably compatible during breastfeeding. (Briggs 2015)
However, other muscle relaxants with a more rapid elimination time period and better known drugs are preferred.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2012 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM