Last update June 29, 2022
Serotonin and Norepinephrine selective re-uptake inhibitor. Used in the treatment of depression. Authorized for treatment of Fibromyalgia in some countries. Oral administration in two daily doses.
Latest update failed to find relevant data on breastfeeding.
According to the manufacturer, it is excreted in breast milk in small amounts. (FDA 2012)
Pharmacokinetic data (low serum protein binding and high bioavailability) indicates that drug excretion into breast milk in significant amount is highly probable. Absorption by the infant is likely to be high as well.
At usual dose it does not induce galactorrhea. (Trenque 2011)
Frequent and potential severe side effects have been found.
Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable, especially during the neonatal period and in the event of prematurity.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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