Last update April 24, 2021
Metamfetamine is a sympathomimetic drug, powerful stimulant of the central nervous system, whose action and uses are similar to dextroamphetamine.
It has been used in the treatment of Attention Deficit Hyperactivity Disorder (ADHD), but above all it is considered an illegal drug (Chomchai, 2016; Bartu, 2009). It is partially metabolized to amphetamine and it has strong psychotic, addiction and abuse potential (Vallersnes 2016, Courtney 2014, Carvalho 2012).
It is excreted in breast milk (Chomchai, 2016; Bartu, 2009), with a slower elimination than in plasma, as the half-life in milk is 40 hours, disappearing completely from the milk 1 day before the values in urine are negative (Chomchai, 2016).
A breastfeeding mother who inhaled methamphetamine was accused of the cot death of her 2-month-old baby, although there has been some question as to whether methamphetamine in milk was the cause (Green, 1996; Ariagno, 1995).
There is little information on the impact of amphetamine abuse on infant development and health (Oei, 2012), but it is known that they are more exposed to social problems, domestic violence, and lower rates of breastfeeding (Shah, 2012, Oei, 2010).
Amphetamines do not cause significant decreases in prolactin levels (DeLeo, 1983). Methamphetamine withdrawal caused increased prolactin secretion (Zorick, 2011).
Its recreational use is strongly discouraged (Oei, 2012). Drug abuse behavior incapacitates the mother for appropriate baby care and poses a life hazard for both the mother and the infant.
To avoid exposure to the infant and minimize the risk, after the last recreational use of amphetamine, it is advisable to wait 85 hours (5 T ½, which eliminates 97% of the substance) before breastfeeding again. For other authors it is enough to wait 48 hours (Bartu, 2009) or 100 hours (Chomchai, 2016) or, more safely, when the detection in the mother's urine is negative (Chomchai, 2016).
Meanwhile, express and discard milk from the breast regularly to maintain production.
Suggestions made at e-lactancia are done by APILAM team, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it.
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