Last update Feb. 12, 2020

Maternal Transplant

Likely Compatibility

Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.

After an organ transplant, immunosuppressive medication should be taken for life to prevent the immune system (defense) from rejecting the transplanted organ as alien.
The patient has a higher risk of infections and greater likelihood of taking antibiotics.

Although not recommended a few years ago (EBPG 2002, Coady 2002), breastfeeding after transplantation is perfectly possible, without side effects for infants (Sarkar 2018, Coscia 2015, Thiagarajan 2013).

Most antibiotics are compatible with breastfeeding.
Most medications used to prevent transplant rejection are compatible with breastfeeding (Sarkar 2018, Constantinescu 2014, Singh 2011, Gardiner 2006, Munoz-Flores 2001, Nyberg 1998, Thiru 1997, Ziegenhagen 1988, Grekas 1984, Coulam 1982).


See below the information of these related products:

  • Azathioprine (Safe substance and/or breastfeeding is the best option.)
  • Ciclosporin (Safe substance and/or breastfeeding is the best option.)
  • Mycophenolate Mofetil (Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.)
  • Prednisone (Safe substance and/or breastfeeding is the best option.)
  • Tacrolimus (Safe substance and/or breastfeeding is the best option.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.
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Other names

Maternal Transplant is also known as


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Maternal Transplant belongs to this group or family:

References

  1. Sarkar M, Bramham K, Moritz MJ, Coscia L. Reproductive health in women following abdominal organ transplant. Am J Transplant. 2018 May;18(5):1068-1076. Abstract
  2. Shah S, Verma P. Overview of Pregnancy in Renal Transplant Patients. Int J Nephrol. 2016;2016:4539342. Abstract
  3. Coscia LA, Constantinescu S, Armenti DP, Moritz MJ. The 25th Anniversary of the National Transplantation Pregnancy Registry. Clin Transpl. 2015;31:57-68. Abstract
  4. Constantinescu S, Pai A, Coscia LA, Davison JM, Moritz MJ, Armenti VT. Breast-feeding after transplantation. Best Pract Res Clin Obstet Gynaecol. 2014 Nov;28(8):1163-73. Abstract
  5. Thiagarajan KM, Arakali SR, Mealey KJ, Cardonick EH, Gaughan WJ, Davison JM, Moritz MJ, Armenti VT. Safety considerations: breastfeeding after transplant. Prog Transplant. 2013 Jun;23(2):137-46. Abstract
  6. Lawrence RM. Circumstances when breastfeeding is contraindicated. Pediatr Clin North Am. 2013 Feb;60(1):295-318. Abstract
  7. Singh M, Qualie J, Currie A, Howarth ES, Khare MM. Is breastfeeding safe with azathioprine? Obstet Med. 2011 Sep;4(3):104-7. Abstract
  8. Gardiner SJ, Begg EJ. Breastfeeding during tacrolimus therapy. Obstet Gynecol. 2006 Feb;107(2 Pt 2):453-5. Abstract
  9. EBPG Expert Group on Renal Transplantation. European best practice guidelines for renal transplantation. Section IV: Long-term management of the transplant recipient. IV.10. Pregnancy in renal transplant recipients. Nephrol Dial Transplant. 2002 Abstract Full text (link to original source) Full text (in our servers)
  10. Coady NT. Maternal transplantation medications during breastfeeding. J Hum Lact. 2002 Abstract
  11. Muñoz-Flores-Thiagarajan KD, Easterling T, Davis C, Bond EF. Breast-feeding by a cyclosporine-treated mother. Obstet Gynecol. 2001 May;97(5 Pt 2):816-8. Abstract
  12. Nyberg G, Haljamäe U, Frisenette-Fich C, Wennergren M, Kjellmer I. Breast-feeding during treatment with cyclosporine. Transplantation. 1998 Abstract
  13. Thiru Y, Bateman DN, Coulthard MG. Successful breast feeding while mother was taking cyclosporin. BMJ. 1997 Abstract Full text (link to original source) Full text (in our servers)
  14. Ziegenhagen DJ, Crombach G, Dieckmann M, Zehnter E, Wienand P, Baldamus CA. [Pregnancy during cyclosporin medication following a kidney transplant]. Dtsch Med Wochenschr. 1988 Abstract
  15. Grekas DM, Vasiliou SS, Lazarides AN. Immunosuppressive therapy and breast-feeding after renal transplantation. Nephron. 1984 Abstract Full text (link to original source) Full text (in our servers)
  16. Coulam CB, Moyer TP, Jiang NS, Zincke H. Breast-feeding after renal transplantation. Transplant Proc. 1982 Abstract

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