Last update April 5, 2025
Compatible
We do not have alternatives for Итраконазол since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
Итраконазол is Itraconazole in Cyrillic.
Is written in other languages:Итраконазол is also known as
Main tradenames from several countries containing Итраконазол in its composition:
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by La Liga de la Leche, España of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is a triazole antifungal used in the treatment of oropharyngeal and vulvovaginal candidiasis, pityriasis versicolor, other dermatophytosis, onychomycosis and systemic fungal infections and some protozoal infections, such as Acanthamoeba keratitis, leishmaniasis and trypanosomiasis. Oral administration.
Its pharmacokinetic data (moderately high molecular weight and high percentage of protein binding) explain the no or minimal passage into milk observed (McNamara 2004), such that a breastfed infant would receive a maximum of 35 micrograms of itraconazole daily, hundreds of times less than the paediatric dose of 5 mg/kg/day. (Briggs 2015, Janssen 2014, Cazzaniga 1996)
In addition, its low oral bioavailability and the alkaline environment of milk hinder its absorption.
It is used for the treatment of fungal infections in children, including premature infants, with good tolerance. (Mahamaytakit 2014, Gupta 2013 and 2003, Dhondt 1992, Bhandari 1992)
Itraconazole significantly increases plasma concentrations of domperidone, which has to be taken into account in case of simultaneous administration of both drugs. (Yoshizato 2012)