Last update March 8, 2022
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Isoxsuprine Hydrochloride in other languages or writings:
Main tradenames from several countries containing Isoxsuprine Hydrochloride in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 100 | % |
Molecular weight | 338 | daltons |
VD | 1.7 - 16.2 | l/Kg |
pKa | 9.65 | - |
Tmax | 1 | hours |
T½ | 1.25 - 2.2 | hours |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Isoxsuprine is a vasodilator that stimulates beta-adrenergic receptors. It has been used to stop uterine contractions in threatened premature labor and in the treatment of cerebral and peripheral vascular diseases. Oral or intravenous administration 3 or 4 times a day.
Since the last update we have not found published data on its excretion in breastmilk.
The paucity of published pharmacokinetic data does not allow prediction of its possible excretion in breast milk. Its high volume of distribution would make it difficult for it to pass into breast milk.
Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable, especially during the neonatal period and in the event of prematurity.