Last update Jan. 9, 2023
Cetrorelix is a synthetic decapeptide antagonist of gonadorelin (gonadotropin-releasing hormone) that is used to prevent luteinizing hormone surges and premature ovulation in women undergoing ovarian stimulation treatment for assisted reproduction in cases of infertility. Subcutaneous administration.
At the date of the last update we did not find any published data on its excretion in breast milk.
Its pharmacokinetic data (high percentage of protein binding, high molecular weight and very wide volume of distribution) make it highly unlikely that significant quantities will pass into breast milk.
Its low oral bioavailability makes it difficult for it to pass to the infant’s plasma via ingested breast milk as, due to its protein nature, it degrades in the gastrointestinal tract and is not absorbed.
We do not have alternatives for Ganirelix Acetate.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2012 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM