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Empagliflozin is a selective and reversible inhibitor of the sodium and glucose co-transporter 2 (SGLT2). It has similar actions to dapagliflozin. It acts by reducing the renal reabsorption of glucose and increasing its elimination via urine (Devi 2017, Scott 2014).
Administered orally once a day.
Since the last update, we have not found published data on its excretion in breast milk.
Its pharmacokinetic characteristics (moderately elevated molecular weight, high plasma protein binding and large volume of distribution: AEMPS 2019, FDA 2016), make it very unlikely its excretion into breast milk in significant amounts.
It has low risk of hypoglycemia in monotherapy, which increases when it is associated with other hypoglycaemic agents (AEMPS 2019, FDA 2016).
Until there is more published data on this drug in relation to breastfeeding, safer known alternatives may be preferable, especially during the neonatal period and in case of prematurity.
Diet, exercise and breastfeeding improve blood glucose levels.
See below the information of this related product: