Last update Nov. 17, 2024
Compatible
We do not have alternatives for Dolutegravir (DTG), Dolutegravir Sodium since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Dolutegravir (DTG), Dolutegravir Sodium in other languages or writings:
Dolutegravir (DTG), Dolutegravir Sodium belongs to this group or family:
Main tradenames from several countries containing Dolutegravir (DTG), Dolutegravir Sodium in its composition:
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by La Liga de la Leche, España of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Dolutegravir is an HIV integrase inhibitor. It is used in combination with other antiretrovirals (tenofovir + emtricitabine or lamivudine) for the treatment of HIV infection and AIDS. Oral administration.
It is excreted in breast milk in clinically insignificant amounts (Aebi 2022, Dickinson 2021, Waitt 2019, Gini 2018, Kobbe 2016) and no problems have been observed in infants whose mothers have taken it. (Malaba 2022, Kobbe 2016)
Plasma levels in these infants were very low, less than 10% of maternal plasma levels. (Aebi 2022, Dickinson 2021, Waitt 2019, Gini 2018, Kobbe 2016)
Authorized use in children over 4 weeks old and weighing at least 3 kg.
During pregnancy and postpartum, combination antiretroviral therapy regimens that include dolutegravir (especially in association with emtricitabine and tenofovir alafenamide) seem safer and more effective in controlling viral load than those that do not (Chinula 2023), and can even be associated only with lamivudine. (Rohr 2024)
See below the information of this related product: