Last update April 7, 2025
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Dexchlorpheniramine Maleate in other languages or writings:
Dexchlorpheniramine Maleate belongs to this group or family:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 25 - 45 | % |
Molecular weight | 391 | daltons |
Protein Binding | 70 | % |
VD | 2.5 - 3.2 | l/Kg |
pKa | 9.2 | - |
Tmax | 2.5 - 6 | hours |
T½ | 20 - 24 | hours |
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2012 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
1st generation antihistamine, alkylamine, with sedative effect. Dextro-isomer of chlorpheniramine, twice as active as chlorpheniramine. Oral administration every 4 to 6 hours.
At the date of last update we found no published data on its excretion in breast milk.
No problems requiring medical attention have been observed in infants born to mothers taking chlorphenamine. (Ito 1993, Paton 1985)
Possible inhibition of breastfeeding in the first weeks after birth due to antiprolactin effect. (WHO 2002, Messinis 1985)
Used in small doses (2 mg once or twice a day) and occasionally, it should not cause problems in breastfeeding (Lactmed). Monitor sleepiness and adequate infant feeding. (Butler 2014, WHO 2002)
For sustained treatment better to use an alternative. (Powell 2007).
Commercialised in polyassociation with expectorants, corticosteroids, antitussives, etc. Avoid drug associations, especially during breastfeeding.
Bed-sharing with the baby is not recommended if taking this medicine. (UNICEF 2013, Landa 2012, ABM 2008, UNICEF 2006)
See below the information of this related product: