Last update April 17, 2016

Ciclopirox Olamine

Compatible

Safe substance and/or breastfeeding is the best option.

Antifungal agent that is used as a component of creams, gels, suspensions or pessaries.

At latest update no published data were found on excretion into breast milk.

Less than 5% of the applied dose is absorbed.
Because the small dose used and low level achieved in the plasma of most topical dermatological preparations make unlikely the passage of significant amounts into breast milk.
Even more, its high plasma protein-binding capacity makes unlikely excretion into milk.

Do not apply on the chest to prevent infant ingestion; otherwise, apply it after a feeding and clean thoroughly with water before the next one.

Alternatives

  • Fluconazole (Safe substance and/or breastfeeding is the best option.)
  • Miconazole (Safe substance and/or breastfeeding is the best option.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Ciclopirox Olamine is also known as Ciclopirox.


Ciclopirox Olamine in other languages or writings:

Tradenames

Main tradenames from several countries containing Ciclopirox Olamine in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. Dermat: 1.3 %
Molecular weight 207 daltons
Protein Binding 98 %
Tmax 6 hours
1.7 hours

References

  1. SMI. Ciclopirox. Product Monograph. 2013 Full text (in our servers)
  2. Medea. Ciclopirox. Ficha técnica. 2010 Full text (in our servers)
  3. Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin. 2006 Abstract
  4. Mactal-Haaf C, Hoffman M, Kuchta A. Use of anti-infective agents during lactation, Part 3: Antivirals, antifungals, and urinary antiseptics. J Hum Lact. 2001 Abstract

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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America

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