Last update Jan. 9, 2023

Cetrorelix Acetate

Low Risk

Possibly safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.

Cetrorelix is a synthetic decapeptide antagonist of gonadorelin (gonadotropin-releasing hormone) that is used to prevent luteinizing hormone surges and premature ovulation in women undergoing ovarian stimulation treatment for assisted reproduction in cases of infertility. It is also used in endometriosis and uterine fibroids. Subcutaneous or intramuscular administration.

At the date of the last update we did not find any published data on its excretion in breast milk.

Its pharmacokinetic data (high percentage of protein binding, high molecular weight and very wide volume of distribution) make it highly unlikely that significant quantities will pass into breast milk.

Its low oral bioavailability makes it difficult for it to pass to the infant’s plasma via ingested breast milk as, due to its protein nature, it degrades in the gastrointestinal tract and is not absorbed.

Similar products of shorter half-life may be preferable.

See below the information of this related product:


  • Ganirelix Acetate (Possibly safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Cetrorelix Acetate in other languages or writings:


Cetrorelix Acetate belongs to this group or family:


Main tradenames from several countries containing Cetrorelix Acetate in its composition:


Variable Value Unit
Oral Bioavail. 0 %
Molecular weight 1.431 daltons
Protein Binding 86 %
VD 1.16 l/Kg
pKa 9.5 -
Tmax 2 hours
62.8 hours


  1. EMD. Cetrorelix. Drug Summary. 2017 Full text (in our servers)
  2. EMA. Cetrorelix. Ficha técnica. 2009 Full text (in our servers)

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