Last update Jan. 2, 2022

بوليجيلين

Compatible

Safe product and/or breastfeeding is the best option.

In polymer of denatured gelatin derived polypeptides linked with urea bridges. It is a plasma substitute that is used as a plasma volume expander in the treatment of hypovolemic shock. Administration by intravenous infusion.

Since the last update we have not found any published data on its excretion in breast milk.

Its very high molecular weight make it highly unlikely that significant quantities will pass into breast milk.

Its null oral bioavailability makes it difficult for it to pass to the infant plasma from ingested breast milk, except in premature infants and in the immediate neonatal period in which there may be greater intestinal permeability.

List of WHO essential medicines: compatible with breastfeeding. (WHO / UNICEF 2002)

Alternatives

We do not have alternatives for بوليجيلين since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

بوليجيلين is Polygeline in Arabic.

Is written in other languages:

بوليجيلين is also known as

Group

بوليجيلين belongs to this group or family:

Tradenames

Main tradenames from several countries containing بوليجيلين in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. ≈ 0 %
Molecular weight 30.000 - 35.000 daltons
VD 0.11 l/Kg
Tmax 4 - 6 hours
5 - 6 hours

References

  1. Lozano Losada, Abner. Coloides. Rev. Col. Anest. 2005 Abstract Full text (link to original source)
  2. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Abstract Full text (link to original source) Full text (in our servers)

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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM