Last update Jan. 25, 2022

Бутриптилина Гидрохлорид

Limited compatibility

Unsafe. Moderate/severe adverse effects. Compatible under certain circumstances. Follow-up recommended. Use safer alternative or discontinue breastfeeding from 5 to 7 T ½ . Read Commentary.

Tricyclic antidepressant derivative of amitriptyline with actions and uses similar to those of amitriptyline. It has marked antimuscarinic and sedative properties. Used in the treatment of depression.

Product with very few bibliographical references and that has been withdrawn from the market worldwide.

Alternatives

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

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Other names

Бутриптилина Гидрохлорид is Butriptyline Hydrochloride in Cyrillic.

Is written in other languages:

Group

Бутриптилина Гидрохлорид belongs to this group or family:

Tradenames

Main tradenames from several countries containing Бутриптилина Гидрохлорид in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 330 daltons
Protein Binding 90 %
Tmax 2.6 - 7.5 hours
T½ 20 hours

References

  1. Bourgouin J, Gagnon MA, Elie R, Dvornik D, Gonzalez R, Kraml M. Butriptyline: human pharmacokinetics and comparative bioavailability of conventional and sustained release formulations. Biopharm Drug Dispos. 1981 Apr-Jun;2(2):123-30. Abstract
  2. Remakus BL, Kessel LJ, Trichtinger MD, Montgomery P, Griffiths JP. Butriptyline (Evadyne) and the Mexican connection. N Engl J Med. 1981 Jun 18;304(25):1543-4. No abstract available. Abstract

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