Last update Jan. 19, 2024
Compatible
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Anidulafungin in other languages or writings:
Main tradenames from several countries containing Anidulafungin in its composition:
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e-lactancia is a resource recommended by La Liga de la Leche, España of Spain
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It is a semi-synthetic lipopeptide antifungal active against Aspergillus and Candida spp. It is used in the treatment of candidemia, esophageal candidiasis, and other forms of invasive candidiasis. intravenous administration.
IIts pharmacokinetic data (large volume of distribution, high molecular weight and high percentage of binding to plasma proteins) explain the minimal passage into breast milk, which is clinically irrelevant. (Eijsink 2024)
No side effects were found in an infant less than one month old of a mother treated with this drug. (Eijsink 2024)
Due to its protein nature, it is inactivated in the gastrointestinal tract, and is not absorbed, (it has virtually no oral bioavailability), which hinders or prevents its transfer from breastmilk to infant, except in premature babies and the immediate neonatal period, when there may be greater intestinal permeability.
Expert authors consider that it is not necessary to interrupt breastfeeding with this treatment (LactMed), which is probably compatible. (Hale)