Last update July 16, 2025

Aloe

Likely Compatibility

Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.

The leaves of the plant are used. It contains hydroxyanthracenes, acemanan and glucomannan. Attributed properties: oral laxative and wound healing and topical cosmetic. Indications Commission E of the German Ministry of Health (Blumenthal 1998) and European Medicines Agency: constipation in short-term treatment. It is a plant widely used during pregnancy or breastfeeding. (Sim 2013, Zaffani 2006)

At the date of the last update, we found no published data on its excretion in breast milk.

Do not use orally (Kopec 1999, WHO 1999): As it is an active laxative containing 1,8-hydroxyanthracene derivatives, it triggers intestinal spasms and pain. Due to its possible passage into milk, it is best to avoid it during breastfeeding. Excessive or chronic use can trigger severe diarrhoea, dehydration and toxic hepatitis (Posadzki 2013, Bunchorntavakul 2013, Amir 2011). Due to the possible risks of genotoxicity associated with the consumption of some hydroxyanthracene derivatives, since 2021 the marketing of food supplements based on acíbar containing aloe-emodin, emodin, danthron and aloe extracts with hydroxyanthracene derivatives has been prohibited (Fitoterapia.net). Aloe vera whole leaf extract is possibly carcinogenic to humans: Group 2B. (IARC 2016)

It is not toxic when applied topically to the skin (Amir 12011). It is used in gel form to treat cracked and/or sore nipples, appearing to be more effective in some studies than the application of olive oil, lanolin or breast milk itself, although there is no conclusive evidence of its efficacy (Wang 2024, Shetty 2024, Maleki 2022, Alamolhoda 2020, As'adi 2018, Saeidi 2015) and also, together with massage and cactus extract, in the treatment of breast stasis. (Meng 2015)

It can cause contact dermatitis and eczema of the nipple and areola. (De Smet 2004, Barankin 2004)

If applied to the breast, it must be washed off thoroughly to prevent the infant from ingesting it: risk of diarrhoea or weaning due to bad taste (Royal 2013, Larimore 2000): in some cultures it is used to induce weaning by applying it to the nipples. (Abu 2013)

Alternatives

  • Lactulose (Safe product and/or breastfeeding is the best option.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Aloe is also known as


Aloe in other languages or writings:

Tradenames

Main tradenames from several countries containing Aloe in its composition:

References

  1. Fitoterapia.net. Vanaclocha B, Cañigueral S. Fitoterapia.net. 1992 - - Disponible en: https://www.fitoterapia.net. Consulted on March 12, 2025 Abstract
  2. Shetty AP, Halemani K, Issac A, Thimmappa L, Shashidhara YN, Mathias E, Dhiraaj S, Radha K, Mishra P, Sharma A. Effectiveness of the Application of Lanolin, Aloe Vera, and Peppermint on Nipple Pain and Nipple Trauma in Lactating Mothers: A Systematic Review and Meta-Analysis. Matern Child Health J. 2024 Dec;28(12):2013-2025. Abstract
  3. Wang RH, Gong JY, Liu PC, Liu LF, Zhang JT, Yao L, Dong Q, Jia SH. Effects of Aloe Gel on Lactating Women with Nipple Trauma. Breastfeed Med. 2024 Jun;19(6):445-450. Abstract
  4. Maleki A, Youseflu S. The Effectiveness of Aloe Vera on Relief of Irritation and Nipple Pain in Lactating Women: Systematic Review and Meta-Analysis. Obstet Gynecol Int. 2022 Nov 7;2022:7430581. Abstract Full text (link to original source)
  5. Alamolhoda S, Mirabi P, Mojab F. Effects of both aloe vera gel and breast milk on the improvement of nipple soreness in lactating women? A randomized controlled trial. J Herb Medicine 2020;21:100327. Abstract
  6. MedlinePlus. Fitoterapia y suplementos para bajar de peso. Información de salud para usted. 2019 Full text (link to original source) Full text (in our servers)
  7. MedlinePlus. Herbal remedies and supplements for weight loss. Trusted Health information for you 2019 Full text (link to original source) Full text (in our servers)
  8. As'adi N, Kariman N. Herbal prevention and treatment of nipple trauma and/or pain in Iranian studies: A systematic review. J Herbmed Pharmacol. 2018;7:168–75. Abstract Full text (link to original source) Full text (in our servers)
  9. IARC - WHO. International Agency for research on Cancer. Some Drugs and Herbal Products. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Volume 108. 2016 Full text (link to original source)
  10. Eshgizade M, Moghaddam M, Moghaddam H, Mahmoudian A, Mesbah M. Comparison of the effect of olive oil, aloe vera extract and breast milk on healing of breast fissure in lactating mothers: a randomized clinical trial. Qom University of Medical Sciences Journal, 2016, 10(3), 19-27. Abstract
  11. Saeidi R, Tafazoli M, Gholami M, Mazloom R. New treatment for nipple soreness in breastfeeding mothers: A clinical trial study. Iran J Neonatol 2015;6:48-51. Abstract Full text (link to original source)
  12. Meng S, Deng Q, Feng C, Pan Y, Chang Q. Effects of massage treatment combined with topical cactus and aloe on puerperal milk stasis. Breast Dis. 2015 Abstract
  13. Posadzki P, Watson LK, Ernst E. Adverse effects of herbal medicines: an overview of systematic reviews. Clin Med (Lond). 2013 Abstract Full text (link to original source)
  14. Abu Hamad BA, Sammour HK. Weaning practices of mothers attending United Nations Relief and Works Agency health centres in the Gaza Governorates. J Adv Nurs. 2013 Abstract
  15. Sim TF, Sherriff J, Hattingh HL, Parsons R, Tee LB. The use of herbal medicines during breastfeeding: a population-based survey in Western Australia. BMC Complement Altern Med. 2013 Abstract Full text (link to original source) Full text (in our servers)
  16. Bunchorntavakul C, Reddy KR. Review article: herbal and dietary supplement hepatotoxicity. Aliment Pharmacol Ther. 2013 Abstract Full text (link to original source) Full text (in our servers)
  17. The Royal Women’s Hospital Victoria Australia. Herbal and Traditional Medicines in Breasfeeding. Fact Sheet. 2013 Full text (link to original source) Full text (in our servers)
  18. Amir LH, Pirotta MV, Raval M. Breastfeeding--evidence based guidelines for the use of medicines. Aust Fam Physician. 2011 Sep;40(9):684-90. Review. Abstract
  19. Zaffani S, Cuzzolin L, Benoni G. Herbal products: behaviors and beliefs among Italian women. Pharmacoepidemiol Drug Saf. 2006 Abstract
  20. De Smet PA. Health risks of herbal remedies: an update. Clin Pharmacol Ther. 2004 Abstract
  21. Barankin B, Gross MS. Nipple and areolar eczema in the breastfeeding woman. J Cutan Med Surg. 2004 Abstract
  22. Larimore WL, Petrie KA. Drug use during pregnancy and lactation. Prim Care. 2000 Abstract
  23. WHO. World Health Organization. Geneva. WHO monographs on selected medicinal plants. Volume I. WHO monographs 1999 Full text (link to original source) Full text (in our servers)
  24. Kopec K. Herbal medications and breastfeeding. J Hum Lact. 1999 Jun;15(2):157-61. Review. No abstract available. Abstract
  25. Blumenthal M, Busse WR, Goldberg A, Gruenwald J, Hall T, Riggins CW, Rister RS, editors. The American Botanical Council. The Complete German Commission E Monographs. Therapeutic Guide to Herbal Medicines. 1st ed. Integrative Medicine Com; Boston, MA, USA: 1998

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