Last update Sept. 26, 2014

5-Aminolevulinic Acid

Likely Compatibility

Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.

It is locally used together with photo-dynamic therapy (especial blue light) as a treatment of Actinic Dermatitis and Basocelular Carcinoma.

At latest update, relevant information on excretion into breast milk was not found.

Absorption through the skin is very low (0.26 % of administered dose), hence, a low or non-significant level in the mother's plasma should be expected.

In case that a complete elimination of drug would be desired, a time period equivalent to ten times a half-life (Mean time) should be observed after drug administration to resume breastfeeding.

In this case it would be equal to 8-10 hours.

In the mean while, pump-and-dump regularly to maintain milk production.

Do not apply it on the breast or cleanse it thoroughly to keep the baby from swallowing.


We do not have alternatives for 5-Aminolevulinic Acid.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

5-Aminolevulinic Acid is also known as


5-Aminolevulinic Acid belongs to this group or family:


Main tradenames from several countries containing 5-Aminolevulinic Acid in its composition:


Variable Value Unit
Oral Bioavail. 50 - 60 %
Molecular weight 131 daltons
0.8 hours


  1. EMEA. Ácido 5-aminolevulínico. Ficha técnica 2011 Full text (in our servers)
  2. Sandberg C, Halldin CB, Ericson MB, Larkö O, Krogstad AL, Wennberg AM. Bioavailability of aminolaevulinic acid and methylaminolaevulinate in basal cell carcinomas: a perfusion study using microdialysis in vivo. Br J Dermatol. 2008 Abstract
  3. McLoone N, Donnelly RF, Walsh M, Dolan OM, McLoone S, McKenna K, McCarron PA. Aminolaevulinic acid diffusion characteristics in 'in vitro' normal human skin and actinic keratosis: implications for topical photodynamic therapy. Photodermatol Photoimmunol Photomed. 2008 Abstract
  4. New Zealand Datasheet. Methyl aminolevulinate. Drug Summary. 2008 Full text (in our servers)
  5. SNS. Aminolevulinato de metilo (ALM). Información Terapéutica. 2005 Full text (in our servers)

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