Last update Nov. 23, 2021

4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

Analgesic and antipyretic. Indicated in the treatment of pain and fever. It has a weak anti-inflammatory effect. Oral, intravenous and rectal administration, every 4, 6 or 8 hours.

It is excreted in very small quantities in breast milk. (AEMPS 2017, GSK 2015, Notarianni 1987, Bitzén 1981, Findlay 1981, Berlin 1980, Hurden 1980) The amount that the infant can receive through breast milk is much lower than the usual pediatric dose.(Lee 1993) 

No problems have been observed in infants whose mothers were taking it,(AEMPS 2017, Ito 1993) except for one case of mild dermatitis in an infant. (Matheson 1985) 

No association has been observed between maternal paracetamol use and neurodevelopmental disorders in infants (autism spectrum disorder, ASD, attention deficit/hyperactivity disorder,ADHD).

The urinary levels of infants have been undetectable. (AEMPS 2017, Berlin 1980) Other authors have measured insignificant levels in urine, but only paracetamol, not their metabolites as in adults.(Notarianni 1987) 

The hepatotoxicity of paracetamol is lower in newborns and small infants due to hepatic immaturity: the low levels of specific cytochrome P-450 enzymes hinder the conversion of the drug into its toxic metabolites. (Reece 2017, Sachs 2013) 

Medication commonly used in Pediatrics, with authorized use in neonates, including premature infants.

American Academy of Pediatrics: medication usually compatible with breastfeeding. (AAP 2001)

List of essential medicines WHO: compatible with breastfeeding. (WHO / UNICEF, 2002) 

The manufacturer (AEMPS 2017, GSK 2015) and expert authors and medical associations consider it compatible with breastfeeding. (Reece 2017, Davanzo 2014, Rowe 2013, Worthington 2013, Sachs 2013, Amir 2011, Zrour 2010, Chen 2010, Østensen 2007, Nice 2004, Bannwarth 2003, Bar-Oz 2003, Janssen 2000, Nice 2000, Spigset 2000, Mitchell 1999, Bodley 1997, Lee 1993, Bitzen 1981, Berlin 1980)

Alternatives

We do not have alternatives for 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol is Paracetamol in Chemical name.

Is written in other languages:

4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol is also known as

Group

4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol belongs to this group or family:

Tradenames

Main tradenames from several countries containing 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition:

  • Acecat
  • Acemuk día y noche™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Acetofen
  • Acetolit
  • Actifed (France)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Actron (France)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Actron Compuesto (Spain)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Adalgur™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Adalgur N™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Adol
  • Adolen™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Ai Er Xing (爱尔星)
  • Ai Sen (爱森)
  • Alador
  • Algicler™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Algidol (Spain)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Algifene (Portugal)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Algiseda™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Algocit
  • Algodol
  • Algofetin (Альгофетин)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Algostase Mono
  • Aliren™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • AnYi (安怡)
  • Anacin Advanced Headache™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Anacin Max™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Anadin
  • Analgilasa™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Anatyl
  • Anticatarral ™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Antidol
  • Antiflu-Des™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Antigrippine (Portugal)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Apap (Апап)
  • Apiredol
  • Apiretal
  • Apogrip™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Apotel
  • Apracur Antifebril
  • Back-Aid™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Basoplex™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Becetamol
  • Bei Le Xin (倍乐信)
  • Ben-u-ron
  • Ben-u-ron (悦诺清)
  • Beseroldos™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Bio Grip-T
  • Bio-Electro, Bio electro, Bioelectro™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Biocetamol
  • Blokium Gesic™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Bregamin AV™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Brevex™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Bufferin (百服宁)
  • Buscapina Compositum N™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Buscapina Compositum NF™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Calgayan™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Calmador Plus™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Calpol (Калпол)
  • Captin
  • Carbafen™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Causalon
  • Cefabrina
  • Cefalex Plus™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Cefalium™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Cefecon D (Цефекон Д)
  • Cibalena A™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Citramon Extra Цитрамон-Экстра™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Citramon Maxi Цитрамон Макси™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Citramon-F Цитрамон-Ф™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Claradol
  • Cloq Plus™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Co-Dafalgan™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Co-dydramol Tablets BP 2020™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Codalgin™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Cold Relief™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Coricidin (United States of America, Venezuela)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Cupanol
  • Curpol
  • DHC Plus™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Dafalgan
  • Dafalganhop
  • Daleron (Далерон)
  • Day & Night™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • DayQuil D™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Depalgos™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Depon
  • Diliban™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Dirox
  • Dolanet™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Dolaren Доларен™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Dolex (Colombia, Uruguay)
  • Dolex Forte (Colombia)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Dolex Gripa (Colombia)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Dolider™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Doliprane
  • Dolipranelib
  • Dolipraneoro
  • Dolko
  • Dolo-Cold™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Dolocatil
  • Dolol-Instant
  • Dolomol (Доломол)
  • Dolostop (Spain)
  • Dolostop Plus™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Dolprone
  • Dolvan™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Doril Enxaqueca™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Dristan (Canada, Turkey)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Dristan Descongestivo™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Dristan Max™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Duaneo
  • Dvorah™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Dymadon
  • Dypracet™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Efetamol
  • Efferaldol con Vitamina C™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Efferalgan
  • Efferalgan (Эффералган)
  • Emagrim™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Endocet™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Enelfa
  • Er He Yi (尔合依)
  • Er Re An (而热安)
  • Excedrin™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Excedrin (Brazil, Canada)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Fan Nuo (凡诺)
  • Fasconal™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Fayrus™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Febrectal
  • Fensum
  • Fiebrol
  • Fiebrolito
  • Fioricet™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Fiorinal (Australia)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Flash
  • Flodigrip C™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Flodigrip Descongestivo™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Flodigrip-NF™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Flutabs (Флютабс)
  • Forsodol (Форсодол)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Fortolin (保达琳)
  • Frenadol™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Frenadol Complex™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Frenadol PS™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Gelocatil
  • Gelocatil Plus™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Gelocatil gripe con pseudoefedrina™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Gelocatil gripe forte con fenilefrina™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Gewamol
  • Goodys Migraine Relief™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Gripex Max (ГрипексМакс)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Grippostad (Austria, Hungary)
  • Grippostad (Czech Republic)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Grippostad Гриппостад™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Hemicraneal™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Infulgan (Инфулган)
  • Invernosan
  • Itedal
  • Izalgi™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Kang Yu Deng Tong (康裕登通)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Kofan (Кофан)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Kratofin simplex
  • Lamaline™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Laritol G™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Lemsip
  • Livzon Ganle (丽珠感乐)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Matrix Migra™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Mejoral (Argentina, Mexico)
  • Mejoral Cafeina™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Melabon (Austria, Spain)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Melabon Infantil (Spain)
  • Melabon K (Germany)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Mexalen
  • Midol Menstrual Complete™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Midrin™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Migrainex™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Migraleve™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Migraleve Pink tablets (Ireland, United Kingdom)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Migrax™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Migretil™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Momentum
  • Naxodol Plus (Chile)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Neo Optalidon (Italy)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Neo-Percodan™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Nodipir
  • Nodolex
  • Norflex Plus™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Norgesic™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Novalgin (Новалгин)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Novo Asat
  • Nupeldol
  • NyQuil Hot Therapy™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • NyQuil Nighttime Cold/Flu™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Oxafem™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • PCM
  • Pa La Xin (帕拉辛)
  • Paedialgon
  • Pamol
  • Panadeine™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Panado
  • Panado Plus™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Panado-Co™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Panadol
  • Panadol (Панадол)
  • Panadol (必理通)
  • Panadol Antigripal™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Panadol Extra™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Panadol Plus™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Panadol Ultra™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Panamax
  • Panodil
  • Para Z Mol
  • Paracetamol Grip NF™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Paraflex Plus™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Parafludeten
  • Parafon Forte™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Parageniol
  • Parahexal
  • Parakapton
  • Paralgin
  • Paramol™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Parapaed
  • Paraspeed
  • Paratral
  • Parcel™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Parenzyme Analgesico™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Parsel™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Pazital™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Peinfort
  • Perdolan
  • Perfalgan
  • Perfalgan (Перфалган)
  • Perfusalgan
  • Pharmagrip Duo™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Pimalev™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Plexicodim™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Plovacal
  • Pontalsic™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Predualito
  • Pu Le Er (普乐尔)
  • Qual™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Rapidol (Рапидол)
  • Refrianex Compuesto™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Relaxophen™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Remedeine™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Resaquit™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Resolvebohm
  • Robaxacet™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Robaxifen™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Robaxisal Compuesto (Spain)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Rosel™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Saldeva forte™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Sanalgin N™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Saridon™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Saridon N (Portugal)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Sensibit D (Mexico)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Sensibit D-NF (Mexico)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Setamol
  • Shi Ning (施宁)
  • Sinpro N
  • Sinutab (Argentina, Belgium, Ireland)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Sinutab Extra (Mexico)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Sinutab II (Portugal)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Sinutab NT (Canada)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Snaplets-FR (斯耐普)
  • Spasmend™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Splentir™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Strimol (Стримол)
  • Su Ting (素廷)
  • Tafirol
  • Tafirol AC™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Tafirol Flex (Argentina)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Tafirol Flex (Mexico)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Tafirol Migra™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Takipirina
  • Talgo
  • Tapsin Analgesico™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Tapsin Antigrippal Polvo Dia™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Tapsin Antigrippal Polvo Noche™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Tapsin Forte Recubiertos™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Tapsin Nocturno™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Tapsin Puro
  • Termaldina Codeina™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Termalgin
  • Termofren
  • Tetradox
  • Tetralgin APC™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Togal
  • Tramacet™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Trezix™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Tylenol
  • Tylenol (泰诺林)
  • Tylenol Back Pain™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Tylenol n1-n2-n3™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Tylenol n4™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Tylex (Brazil, Ireland, United Kingdom)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Tylex (Mexico, Venezuela)
  • Tylex CD (Mexico, Venezuela)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Tylex Flu (Mexico)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Tylox™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Ultracet™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Ultracet (及通安)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Unebril
  • Vicks DayQuil Multi-Symptom Cold/Flu Relief™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Vicks NyQuil Multi-Symptom Cold Flu Relief™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Vicks Sinex (United Kingdom)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Viclor
  • Vincigrip™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • XL-3 VR™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Xing Le Ning (兴乐宁)
  • Xolox™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Xumadol
  • Yi Di Qing (一滴清)
  • Yi Li Miao (宜利妙)
  • Yi Shang (易尚)
  • Zaldiar™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Zaldiar (Залдіар)™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition
  • Zolben C™. Contains other elements than 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-P-Aminophenol in its composition

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 75 - 85 %
Molecular weight 151 daltons
Protein Binding 10 - 25 %
VD 1 l/Kg
pKa 9.5 -
Tmax 0.2 - 2 hours
1 - 3 hours
M/P ratio 0.9 - 1.4 -
Theoretical Dose 1.5 - 2.25 mg/Kg/d
Relative Dose 2.3 - 5.2 %
Ped.Relat.Dose 2.5 - 3.75 %

References

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  2. AEMPS. Paracetamol. Ficha técnica. 2017 Full text (in our servers)
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  9. Amir LH, Pirotta MV, Raval M. Breastfeeding--evidence based guidelines for the use of medicines. Aust Fam Physician. 2011 Sep;40(9):684-90. Review. Abstract Full text (link to original source) Full text (in our servers)
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  12. Zrour-Hassen S, Jguirim M, Aouam K, Korbaa W, Younes M, Bejia I, Touzi M, Bergaoui N. [Safety of rheumatic disease drugs at childbearing age]. Therapie. 2010 Abstract
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  15. Bar-Oz B, Bulkowstein M, Benyamini L, Greenberg R, Soriano I, Zimmerman D, Bortnik O, Berkovitch M. Use of antibiotic and analgesic drugs during lactation. Drug Saf. 2003 Abstract
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  17. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Full text (link to original source) Full text (in our servers)
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