Last update Sept. 2, 2022
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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1-(3,5-Dihydroxyphenyl)-2-(4-hydroxy-α-methylphenethylamino)ethanol is Fenoterol in Chemical name.
Is written in other languages:1-(3,5-Dihydroxyphenyl)-2-(4-hydroxy-α-methylphenethylamino)ethanol is also known as
1-(3,5-Dihydroxyphenyl)-2-(4-hydroxy-α-methylphenethylamino)ethanol belongs to these groups or families:
Main tradenames from several countries containing 1-(3,5-Dihydroxyphenyl)-2-(4-hydroxy-α-methylphenethylamino)ethanol in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 2 | % |
Molecular weight | 303 | daltons |
VD | 0.7 - 1.2 | l/Kg |
pKa | 8.85 | - |
Tmax | 2 | hours |
T½ | 0.25 - 0.9 | hours |
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
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Fenoterol is a direct-acting sympathomimetic with beta2 adrenergic agonist activity. It is used as a bronchodilator in asthma and in the treatment of preterm labor. Oral, inhaled or intravenous administration.
Since the last update we have not found published data on its excretion in breastmilk.
Its very low oral bioavailability, 2% (Hochhaus 1992), minimizes the passage into plasma of the infant from ingested breast milk, except in the premature and in the immediate neonatal period in which there may be greater intestinal permeability.
Other bronchodilators with similar structure and properties, such as terbutaline, are excreted in negligible amounts in breast milk.
Fenoterol administration in preterm labor has no effect on the secretory concentration of IgA in breast milk. (Martell 1985)