Last update Aug. 29, 2021

Zinc Salts

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

Zinc (Zn) is an essential element of nutrition. It is present in many foods.
The daily needs of Zn are 8 to 15 mg (Hall Moran 2010) and depend on the daily intake of phytates. In nursing mothers they are 11 mg for low intakes of phytate (≤ 330 mg/day) and 14 mg/day for high intakes (≥ 990 mg/day) of phytate (Haase 2020).

There are millions of people in the world with Zn deficiency.
It is used as a treatment in Wilson’s disease and acrodermatitis enteropathica.

Zn intervenes in the process of regulation of lactation (Lee 2016).
Pasteurization of breast milk does not affect the concentration of Zn or other trace elements (Mohd-Taufek 2016).

The mean Zn concentration in breast milk is 4 to 16 mg/L (Picciano 1976, Hannan 2005, Dórea 2012) and is independent of plasma levels and daily maternal intake (Krebs 1995, Chierici 1999, Hannan 2009).
The intestinal absorption of zinc almost doubles during pregnancy and lactation (Fung 1997).
Infant zinc levels depend on zinc levels in breast milk (Dumrongwongsiri 2015)
With a varied and balanced diet, mineral supplements are not necessary. Excess ingestion of zinc can lead to gastric, intestinal and pancytopenia problems (Irving 2003).


See below the information of this related product:

  • Fytate; Phytate (Possibly safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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Other names

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Group

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Tradenames

Main tradenames from several countries containing Zinc Salts in its composition:

List of 28 tradenames

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 20 - 30 %
Molecular weight 65 daltons
Theoretical Dose 0.0004 mg/Kg/d
Relative Dose 0.12 %

References

  1. Keikha M, Shayan-Moghadam R, Bahreynian M, Kelishadi R. Nutritional supplements and mother's milk composition: a systematic review of interventional studies. Int Breastfeed J. 2021 Jan 4;16(1):1. Abstract Full text (link to original source)
  2. Haase H, Ellinger S, Linseisen J, Neuhäuser-Berthold M, Richter M; German Nutrition Society (DGE).. Revised D-A-CH-reference values for the intake of zinc. J Trace Elem Med Biol. 2020 Apr 23;61:126536. Abstract
  3. Gibson RS, King JC, Lowe N. A Review of Dietary Zinc Recommendations. Food Nutr Bull. 2016 Abstract
  4. Lee S, Kelleher SL. Molecular regulation of lactation: The complex and requisite roles for zinc. Arch Biochem Biophys. 2016 Abstract
  5. Mohd-Taufek N, Cartwright D, Davies M, Hewavitharana AK, Koorts P, McConachy H, Shaw PN, Sumner R, Whitfield K. The effect of pasteurization on trace elements in donor breast milk. J Perinatol. 2016 Abstract
  6. Abe SK, Balogun OO, Ota E, Takahashi K, Mori R. Supplementation with multiple micronutrients for breastfeeding women for improving outcomes for the mother and baby. Cochrane Database Syst Rev. 2016 Abstract
  7. Ares Segura S, Arena Ansótegui J, Díaz-Gómez NM; en representación del Comité de Lactancia Materna de la Asociación Española de Pediatría. La importancia de la nutrición materna durante la lactancia, ¿necesitan las madres lactantes suplementos nutricionales? [The importance of maternal nutrition during breastfeeding: Do breastfeeding mothers need nutritional supplements?] An Pediatr (Barc). 2015 Abstract Full text (link to original source) Full text (in our servers)
  8. Dumrongwongsiri O, Suthutvoravut U, Chatvutinun S, Phoonlabdacha P, Sangcakul A, Siripinyanond A, Thiengmanee U, Chongviriyaphan N. Maternal zinc status is associated with breast milk zinc concentration and zinc status in breastfed infants aged 4-6 months. Asia Pac J Clin Nutr. 2015 Abstract
  9. Severi C, Hambidge M, Krebs N, Alonso R, Atalah E. Zinc in plasma and breast milk in adolescents and adults in pregnancy and pospartum: a cohort study in Uruguay. Nutr Hosp. 2013 Abstract
  10. Izumi Y. Can mothers with Wilson's disease give her breast milk to their infant? Teikyo Med J. 2012;35:17-24. 2012 Full text (link to original source) Full text (in our servers)
  11. Dórea JG. Zinc and copper concentrations in breastmilk. Indian Pediatr. 2012 Abstract
  12. Ejezie F, Nwagha U. Zinc Concentration during Pregnancy and Lactation in Enugu, South-East Nigeria. Ann Med Health Sci Res. 2011 Abstract
  13. Hall Moran V, Lowe N, Crossland N, Berti C, Cetin I, Hermoso M, Koletzko B, Dykes F. Nutritional requirements during lactation. Towards European alignment of reference values: the EURRECA network. Matern Child Nutr. 2010 Oct;6 Suppl 2:39-54. Abstract Full text (link to original source) Full text (in our servers)
  14. Hannan MA, Faraji B, Tanguma J, Longoria N, Rodriguez RC. Maternal milk concentration of zinc, iron, selenium, and iodine and its relationship to dietary intakes. Biol Trace Elem Res. 2009 Abstract
  15. Hannan MA, Dogadkin NN, Ashur IA, Markus WM. Copper, selenium, and zinc concentrations in human milk during the first three weeks of lactation. Biol Trace Elem Res. 2005 Abstract
  16. Irving JA, Mattman A, Lockitch G, Farrell K, Wadsworth LD. Element of caution: a case of reversible cytopenias associated with excessive zinc supplementation. CMAJ. 2003 Abstract
  17. Institute of Medicine (US) Panel on Micronutrients. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington (DC): National Academies Press (US); 2001. Abstract Full text (link to original source)
  18. Chierici R, Saccomandi D, Vigi V. Dietary supplements for the lactating mother: influence on the trace element content of milk. Acta Paediatr Suppl. 1999 Abstract
  19. Doran L, Evers S. Energy and nutrient inadequacies in the diets of low-income women who breast-feed. J Am Diet Assoc. 1997 Abstract
  20. Fung EB, Ritchie LD, Woodhouse LR, Roehl R, King JC. Zinc absorption in women during pregnancy and lactation: a longitudinal study. Am J Clin Nutr. 1997 Abstract
  21. Itriago A, Carrión N, Fernández A, Puig M, Dini E. [Zinc, copper, iron, calcium, phosphorus and magnesium content of maternal milk during the first 3 weeks of lactation]. Arch Latinoam Nutr. 1997 Abstract
  22. Krebs NF, Reidinger CJ, Hartley S, Robertson AD, Hambidge KM. Zinc supplementation during lactation: effects on maternal status and milk zinc concentrations. Am J Clin Nutr. 1995 Abstract
  23. Picciano MF, Guthrie HA. Copper, iron, and zinc contents of mature human milk. Am J Clin Nutr. 1976 Abstract

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