Last update Dec. 4, 2020
Very Low Risk
A nucleoside analog, structurally related to thymidine. Reverse transcriptase enzyme inhibitor with anti-HIV activity.
Oral administration in two daily doses. Intravenous presentation is also possible.
It is excreted in breastmilk in clinically insignificant amounts (Corbett 2014, Shapiro 2013 and 2005, Palombi 2012, Mirochnick 2009, Giuliano 2007)
No problems have been observed in infants whose mothers took it (Shapiro 2005).
Except in one case (Shapiro 2005), the plasma levels of these infants were undetectable (Corbett 2014, Palombi 2012, Mirochnick 2009) or very low (Palombi 2012).
According to the policy adopted by the health authorities of each country, breastfeeding in mothers with HIV/AIDS may or may not be recommended.
With highly active antiretroviral therapy (HAART), the HIV viral load can be reduced to zero, reducing the risk of HIV transmission through breastfeeding to levels similar to those of formula feeding.
We do not have alternatives for Zidovudine (ZDV) since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it.
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