Last update Dec. 7, 2022
Very Low Risk
Coumarin-type anticoagulant drug vitamin K antagonist used for the treatment and prophylaxis of thromboembolic disorders. It works by depressing the hepatic synthesis of vitamin K-dependent coagulation factors.Oral or intravenous administration. Initially it was used as a rodenticide.
Warfarin is detected in breast milk in null or clinically insignificant amounts. (McKenna 1983, Orme 1979 y 1977, De Swiet 1977)
Not problems have been observed in infants whose mothers were treated. (Ito 1993, McKenna 1983)
Plasma levels of warfarin in such infants were undetectable. (Ito 1993, McKenna 1983)
Even in cases of accidental maternal overdosing, infants did not show any clinical problem and/or coagulation tests were not altered. (Schindler 2011)
Several medical societies and experts authors consider the use of this medication to be safe or very probably safe during breastfeeding. (LactMed, Azenkot 2022, Sucker 2020, Bates 2018, 2012 & 1997, Schaefer 2015, Marshall 2014, Rowe 2013, Fuller 2013, Yurdakök 2012, Middeldorp 2011, Amir 2011, Dresang 2008, Clark 2000, Greer 1998, Letsky 1997, Leys 1997, Hirsh 1995, Olthof 1993, Ginsberg 1988)
American Academy of Pediatrics: medication usually compatible with breastfeeding (AAP 2001). Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs: compatible with Breastfeeding. (WHO 2002)
We do not have alternatives for Warfarin since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2006 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM