Vilanterol Trifenatate

Bronchodilator with similar characteristics to salbutamol and terbutaline, but with prolonged action like salmeterol. Use in combination with fluticasone and/or umeclidinium in the treatment of asthma. Inhaled administration.

As of the last update, we found no published data on its excretion in breast milk.

Its pharmacokinetic data (large volume of distribution, moderately high molecular weight and high percentage of protein binding) make it very unlikely to pass into breast milk in clinically significant quantities.

Its low oral bioavailability makes it difficult to pass into infant plasma from ingested breast milk, except in premature infants and the immediate neonatal period in which there may be greater intestinal permeability.

Terbutaline, a molecule of the same family, is excreted in negligible amounts in breast milk.

Several medical societies and expert authors consider safe the use of inhaled bronchodilators during lactation due to the low maternal serum levels reached. ^{(Lactmed, Bendien 2024, National Asthma 2004, Nelson 2001, Ellsworth 1994)}